Combining Precursor and Fragment Information for Improved Detection of Differential Abundance in Data Independent Acquisition |
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| Institution: | 3. Northeastern University, Boston MA 02115;4. Biognosys, Wagistrasse 21, 8952 Schlieren, Switzerland;5. Thermo Fisher Scientific, 28199 Bremen, Germany |
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| Abstract: |  Download : Download high-res image (233KB)Download : Download full-size imageHighlights- ?Modern DIA methods contain high quality MS1 and MS2.
- ?We developed a statistical procedure incorporating MS1 and MS2.
- ?Benchmarking, the combined method outperformed the individual use of MS1 or MS2.
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| Keywords: | Quantification Mass Spectrometry SWATH-MS Cancer Biomarker(s) Lung Cancer Label-Free Quantification |
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