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DEqMS: A Method for Accurate Variance Estimation in Differential Protein Expression Analysis

Institution:	3. Department of Oncology-Pathology, Science for Life Laboratory, Karolinska Institutet, Stockholm, Sweden;4. Institute for Molecular Medicine, University of Helsinki, Helsinki, Finland;5. Centre for Molecular Biology of Heidelberg University (ZMBH), Heidelberg, Germany

Abstract:	Download : Download high-res image (302KB) Download : Download full-size image Highlights ?DEqMS is a method for statistical analysis of quantitative MS-data. ?Variance estimates based on the actual MS-data structure. ?Improved statistical power and accuracy in protein differential analysis. ?DEqMS is available as a user-friendly R package in Bioconductor.

Keywords:	Quantification label-free quantification statistics data evaluation mass spectrometry quality control and metrics differential analysis FDR TMT
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