Proteaphagy in Mammalian Cells Can Function Independent of ATG5/ATG7 |
| |
| Affiliation: | Institute for Biochemistry and Molecular Biology, Medical Faculty, University of Bonn |
| |
| Abstract: |  Download : Download high-res image (123KB)Download : Download full-size imageHighlights- •Quantitative proteomics of isolated lysosomes, autophagosomes and proteasomes.
- •Pharmacological inhibition of proteasomes leads to their accumulation within lysosomes.
- •Inhibition of classical autophagy pathways cannot completely block this process.
- •Known autophagy adaptor proteins are not involved.
|
| |
| Keywords: | Proteases protein degradation protein turnover autophagy subcellular analysis lysosome proteasome |
| 本文献已被 ScienceDirect 等数据库收录！ |
