An Interaction Network of RNA-Binding Proteins Involved in Drosophila Oogenesis期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

An Interaction Network of RNA-Binding Proteins Involved in Drosophila Oogenesis

Authors:	Prashali Bansal Johannes Madlung Kristina Schaaf Boris Macek Fulvia Bono

Affiliation:	1. Living Systems Institute, University of Exeter, Exeter, UK;2. Max Planck Institute for Developmental Biology, Tübingen, Germany;3. Proteome Center Tübingen, Interfaculty Institute for Cell Biology, Eberhard Karls University, Tübingen, Germany

Abstract:	Download : Download high-res image (92KB) Download : Download full-size image Highlights •Label-free and dimethyl labeling MS analysis of 6 RBPs from Drosophila ovaries. •Functionally related RBPs show overlapping proteomes. •Selective co-purification of splicing factors and translational regulators. •Validation of 26 novel interactions by co-immunoprecipitation.

Keywords:	Developmental biology Drosophila melanogaster ribonucleoproteins mass spectrometry macromolecular complex analysis macromolecular assemblages RBPs RNA localization
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