Regional localization of the gene for thyroid peroxidase to human chromosome 2pter----p12 |
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| Authors: | J J de Vijlder C Dinsart F Libert A Geurts van Kessel H Bikker P A Bolhuis G Vassart |
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| Affiliation: | Academic Medical Center, University of Amsterdam, The Netherlands. |
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| Abstract: | A 2.0-kb thyroid peroxidase cDNA of human origin was used as probe for Southern blot hybridization of genomic DNA from human somatic cells and human-rodent somatic cell hybrids. The results showed that the gene coding for human thyroid peroxidase is located on chromosome. 2. Further analysis of hybrids derived from Burkitt lymphoma cells carrying a (2;8)(p12;q24) translocation revealed that the gene maps to the region 2pter----p12. |
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