The Interaction of the rad201Gene with Genes mei-9and mei-41in Germline Cells of DrosophilaFemales |
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Authors: | S V Sarantseva Yu M Khromykh |
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Institution: | (1) St. Petersburg Konstantinov Institute of Nuclear Physics, Gatchina, Leningrad oblast, 188350, Russia |
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Abstract: | The effect of Drosophilamutation rad201
G1together with mutations mei-41
D5and mei-9
aon the sensitivity of oocytes to induction of dominant lethals (DLs) was studied. To this end, the frequencies of spontaneous and gamma-radiation-induced DLs in consecutive egg batches of females carrying double or single mutations were estimated. Since the effects of the mutations examined are expressed only at the previtellogenetic stages of oogenesis, only newly hatched (0–5-hour-old) females, whose oocytes did not develop farther than stage 7, were irradiated. The results obtained indicated that in intact and irradiated oocytes of double mutants mei-9
a
rad201
G1and mei-41
D5
rad201
G1, mutation rad201
G1epistatically suppresses the mutations of the both meigenes. |
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Keywords: | |
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