Involvement of apolipoprotein E in the hematogenous route of herpes simplex virus type 1 to the central nervous system |
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| Authors: | Burgos Javier S Ramirez Carlos Sastre Isabel Bullido María J Valdivieso Fernando |
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| Affiliation: | Departamento de Biología Molecular and Centro de Biología Molecular Severo Ochoa (C.S.I.C.-U.A.M.), Universidad Autónoma de Madrid, Cantoblanco, 28049 Madrid, Spain. |
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| Abstract: | Apolipoprotein E (ApoE), a constituent of the lipoproteins, may be relevant in herpes simplex virus type 1 (HSV-1) infection of the central nervous system (CNS), since HSV-1 binds to human serum ApoE lipoproteins. This study demonstrates the involvement of ApoE in the hematogenous route of HSV-1 to the CNS. |
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