Plasmodium gallinaceum: response of malarious chicken embryos to injection of serum from hyperimmunized chickens. |
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Authors: | R B McGhee |
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Affiliation: | Department of Zoology, University of Georgia, Athens, Georgia 30602 U.S.A. |
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Abstract: | The injection of serum from chickens hyperimmune to the avian malaria parasite, Plasmodium gallinaceum, or of nonimmune serum into the chorioallantoic cavity of chicken embryos infected with the same parasite resulted in changes in the blood picture of such embryos. In those embryos receiving serum from hyperimmunized birds: The level and rate of parasite increase were depressed; the maturation of the erythroid elements was reduced; the hematocrit values increased only by 27% as compared with 69% in untreated embryos. While hematocrit levels and rates of erythrocytic maturation were depressed in those embryos injected with nonimmune serum, there was no suppression of parasitemia. The results suggest a definite role of immunity in the anemia accompanying malaria. |
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Keywords: | Chicken embryos Chickens Acquired immunity Induction of anemia Erythrocytes Immunopathology Malaria Protozoa Embryology |
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