Geographical variation in defensive chemicals from pacific coast dorid nudibranchs and some related marine molluscs |
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| Institution: | 1. Scripps Institution of Oceanography (A-012F), University of California at San Diego, La Jolla, CA 92093, U.S.A.;2. Departments of Chemistry and Oceanography, University of British Columbia, Vancouver, British Columbia V6T 1W5, Canada;1. School of Traditional Chinese Pharmacy and State Key Laboratory of Natural Medicines, China Pharmaceutical University, Nanjing 211198, PR China;2. State Key Laboratory of Phytochemistry and Plant Resources in West China, Kunming Institute of Botany, Chinese Academy of Sciences, Kunming 650201, PR China;3. YMU-HKBU Joint Laboratory of Traditional Natural Medicine, Yunnan Minzu University, Kunming 650500, PR China;1. Cancer Cell Biology Research Group, Department of Pathology and Experimental Therapeutics, Faculty of Medicine, University of Barcelona, Barcelona, Spain;2. Laboratory of Signal Transduction, Department of Medical Sciences, Institute for Research in Biomedicine – iBiMED, Health Sciences Program, University of Aveiro, Aveiro, Portugal;3. Department of Chemistry, University of Burgos, Burgos, Spain;1. School of Computer & Software, Nanjing University of Information Science & Technology, Jiangsu, Nanjing 210-044, China;2. Huafeng Meteorological Media Group, Beijing 100-080, China;3. Xinjiang University, Urumqi 830-008, China;4. Dept. Computer Science, KingSaud University, Riyadh 11362, Saudi Arabia;1. Department of Pharmaceutical Chemistry, College of Pharmacy, King Saud University, PO Box 2457, Riyadh 11451, Saudi Arabia;2. Department of Tanning Materials and Leather Technology, National Research Centre, 33 El-Bohouth St. (Former El-Tahrir St.), Dokki, Cairo 12622, Egypt;3. Medicinal Aromatic, and Poisonous Plants Research Center, College of Pharmacy, King Saud University, PO Box 2457, Riyadh, 11451, Saudi Arabia;4. Department of Chemistry, Faculty of Science and Technology, El-Neelain University, P.O. Box 12702, Khartoum 11121, Sudan;5. Department of Pharmaceutical Chemistry, Drug Exploration and Development Chair (DEDC), College of Pharmacy, King Saud University, Riyadh 11451, Saudi Arabia;6. Peptide Chemistry Department, Chemical Industries Research Division, National Research Centre, 33 El-Bohouth St. (Former El-Tahrir St.), Dokki, Cairo 12622, Egypt |
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| Abstract: | 1. Comparison of the chemical constituents of geographically diverse collections of six dorid nudibranchs has revealed that those species that are capable of de novo biosynthesis of defensive metabolites always produce the same array of chemicals.2. Conversely, those species that acquire chemicals from their sponge diet have a variable chemical arsenal.3. It is proposed that chemical consistency be used as an indicator of the origin of chemicals in the defensive arsenal of dorid nudibranchs. |
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