EBV seroepidemiology in married and unmarried women and men in Iran |
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| Authors: | Morteza Pourahamad Farhang Hooshmand Sara Olyaee Nezhad Abdolali Sepidkar |
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| Institution: | 1.Department of Internal Medicine, Jahrom University of Medical Sciences, Iran. ;2.Department of Pathology, Jahrom University of Medical Sciences, Iran.;3.Medical Student, Jahrom University of Medical Sciences, Iran.;4.Student Research Committee, Jahrom University of Medical Sciences, Iran.;5.Department of Surgery, Jahrom University of Medical Sciences, Iran. |
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| Abstract: | Background:Among the eight known human herpes viruses, Epstein- Barr virus (EBV) is considered to be sexually transmissible. This study was conducted to evaluate the seroepidemiology of this infection in married and unmarried Iranian couples. Methods:In this comparative observational and cross-sectional study, 160 men and women were divided into married and unmarried groups. Serum IgG and IgM antibodies to the EBV viral capsid antigen were analyzed by Enzyme-linked Immunosorbent Assays (ELISAs).Results:In this study 78 men and 82 women were enrolled. Ninety percent of the married and 76.2% of the unmarried women were anti-EBV IgG positive (P = 0.08), while 80% of the married and 94% of the unmarried men were antiEBV IgG positive (P = 0.052). Conclusion:Seroepidemiology of EBV is not significantly different in married vs. unmarried women and men in Iran; therefore, sexual contact may not be the primary mechanism of EBV transmission in Iran and other developing countries. Attention to other possible routes of transmission is recommended. Key Words: Epstein Barr Virus, Sexual contact, Anti-VCA |
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