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Bone regeneration and stem cells
Authors:Arvidson K  Abdallah B M  Applegate L A  Baldini N  Cenni E  Gomez-Barrena E  Granchi D  Kassem M  Konttinen Y T  Mustafa K  Pioletti D P  Sillat T  Finne-Wistrand A
Institution:Department of Clinical Dentistry, Center for Clinical Resarch, Faculty of Medicine and Dentistry, University of Bergen, Bergen, Norway. kristina.arvidson@iko.uib.no
Abstract:This invited review covers research areas of central importance for orthopaedic and maxillofacial bone tissue repair, including normal fracture healing and healing problems, biomaterial scaffolds for tissue engineering, mesenchymal and foetal stem cells, effects of sex steroids on mesenchymal stem cells, use of platelet-rich plasma for tissue repair, osteogenesis and its molecular markers. A variety of cells in addition to stem cells, as well as advances in materials science to meet specific requirements for bone and soft tissue regeneration by addition of bioactive molecules, are discussed.
Keywords:bone regeneration  stem cells  biomaterials  polymers  regenerative medicine
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