Effects of potassium on vanadate inhibition of sarcoplasmic reticulum Ca2+-ATPase from dog cardiac and rabbit skeletal muscle. |
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| Authors: | T Wang L I Tsai R J Solaro A O Grassi de Gende A Schwartz |
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| Affiliation: | Department of Pharmacology and Cell Biophysics, University of Cincinnati, College of Medicine, Cincinnati, Ohio 45267 USA |
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| Abstract: | The concentration of vanadate for half maximal inhibition of dog cardiac and rabbit skeletal SR Ca2+-ATPase was approximately 5 μM. Preincubation of the enzyme with vanadate resulted in greater inhibition. Effects of potassium on the inhibition were studied under various conditions. |
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