灵芝多糖的生物合成和发酵调控 |
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引用本文: | 刘高强,赵艳,王晓玲,朱朝阳.灵芝多糖的生物合成和发酵调控[J].菌物学报,2011,30(2):198-205. |
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作者姓名: | 刘高强 赵艳 王晓玲 朱朝阳 |
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作者单位: | 中南林业科技大学生命科学与技术学院,林业生物技术湖南省重点实验室,长沙,410004 |
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基金项目: | 国家自然科学基金(No. 30700552);教育部高校博士点基金(No. 20094321120003);湖南省研究生科研创新基金资助项目(No. CX2010B315) |
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摘 要: | 灵芝多糖是灵芝的关键药效成分之一。从灵芝多糖的结构和构效关系、灵芝多糖的单糖组成,灵芝主要多糖IPS-1-1的基本合成途径,以及灵芝多糖的深层发酵调控策略和方法等方面,综述了灵芝多糖生物合成和发酵调控方面的新进展。并对今后的主要研究方向进行了展望。
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关 键 词: | 药用真菌 灵芝 生物合成 深层发酵 发酵策略 |
Biosynthesis and fermentation control of polysaccharides from Ganoderma lucidum |
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Authors: | LIU Gao-Qiang ZHAO Yan WANG Xiao-Ling and ZHU Chao-Yang |
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Institution: | Hunan Provincial Key Laboratory of Forestry Biotechnology, College of Life Science and Technology, Central South University of Forestry & Technology, Changsha 410004, China;Hunan Provincial Key Laboratory of Forestry Biotechnology, College of Life Science and Technology, Central South University of Forestry & Technology, Changsha 410004, China;Hunan Provincial Key Laboratory of Forestry Biotechnology, College of Life Science and Technology, Central South University of Forestry & Technology, Changsha 410004, China;Hunan Provincial Key Laboratory of Forestry Biotechnology, College of Life Science and Technology, Central South University of Forestry & Technology, Changsha 410004, China |
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Abstract: | Ganoderma lucidum polysaccharides (GPS) are of the key pharmacologically active components of this medicinal fungus. Structure-activity relationship, constituents of monosaccharides of GPS, and basic biosynthetic pathways of the key GPS, IPS-1-1, as well as strategies and methods of fermentation control of GPS were reviewed. Further, future orientation in development of biosynthesis and fermentation control of GPS was discussed. |
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Keywords: | medicinal fungi Ganoderma lucidum biosynthesis submerged fermentation fermentation strategies |
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