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Efficient de novo assembly and modification of large DNA fragments |
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| Authors: | Jiang Shuangying Tang Yuanwei Xiang Liang Zhu Xinlu Cai Zelin Li Ling Chen Yingxi Chen Peishuang Feng Yuge Lin Xin Li Guoqiang Sharif Jafar Dai Junbiao |
| Affiliation: | 1.CAS Key Laboratory of Quantitative Engineering Biology, Guangdong Provincial Key Laboratory of Synthetic Genomics and Shenzhen Key Laboratory of Synthetic Genomics, Shenzhen Institute of Synthetic Biology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen, 518055, China ;2.College of Life Sciences, University of Chinese Academy of Sciences, Beijing, 100049, China ;3.Developmental Genetics Laboratory, RIKEN Center for Integrative Medical Sciences (IMS), Yokohama, 230-0045, Japan ; |
| Abstract: | Science China Life Sciences - Synthetic genomics has provided new bottom-up platforms for the functional study of viral and microbial genomes. The construction of the large, gigabase (Gb)-sized... |
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