β-lipotropin-like material in human pancreas and pyloric antral mucosa |
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Authors: | GE Feurle U Weber V Helmstaedter |
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Institution: | Medizinische Poliklinik, University of Heidelberg, D 6900 Heidelberg, Hospitalstraβe 3, Federal Republic of Germany |
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Abstract: | Evidence for the presence of the endogenous opioid precursor β-lipotropin has been found in human pyloric antral mucosa and pancreas by radioimmunochemical displacement curves, Sephadex chromatography, ion exchange chromatography, and immunocytochemistry. Endogenous opioids are not only present in the pituitary gland and nervous tissue but also in the stomach and pancreas, supporting the concept of a common neuro-endocrine system present in brain and gut. |
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