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A technique for hypophysectomy of neonatal rats
Authors:Gregory F Glasscock
Institution:Department of Physiology - Anatomy University of California, Berkeley, CA 94720, USA
Abstract:A new technique for hypophysectomy of 4 to 6 day old neonatal rats is described. A success rate of 82% was obtained on 6 day old neonates, and they showed a 50% reduction in growth rate. The advantages of this new technique are discussed. It provides a method for directly studying the pituitary contribution to development in the preweaned rat pup.
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