Studies on satellite nucleoli in rat hepatocytes and Novikoff hepatoma cells |
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| Authors: | Prof K Smetana R L Ochs R K Busch L C Yeoman H Busch |
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| Institution: | (1) Department of Pharmacology, Baylor College of Medicine, Houston, USA;(2) Institute of Hematology and Blood Transfusion, Prague, Czechoslovakia;(3) Institute of Hematology and Blood Transfusion, U nemocnice 1, CS-128 20 Prague 2 |
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| Abstract: | Summary The present study was undertaken to provide information on the presence and frequency of satellite nucleoli in cells with increased nucleolar biosynthetic activity. The number of hepatocytes containing satellite nucleoli was analyzed in rat liver, regenerating liver 18 h after partial hepatectomy and in Novikoff hepatoma ascites cells. In comparison with hepatocytes of normal liver, the number of both stimulated hepatocytes and malignant hepatoma cells containing satellite nucleoli was significantly reduced. The results also indicated that whereas most satellite nucleoli contain protein C23, a smaller percentage contain protein B23. |
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| Keywords: | Satellite nucleoli Normal stimulated and malignant hepatocytes Rat |
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