The twisted pharynx phenotype in <Emphasis Type="Italic">C. elegans</Emphasis> |
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| Authors: | Claes Axäng Manish Rauthan David H Hall Marc Pilon |
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| Institution: | 1.Dept. of Chemical and Biological Engineering, Lundberg Laboratory,Chalmers University,G?teborg,Sweden;2.Dept. Neuroscience,Albert Einstein College of Medicine,Bronx, New York,USA;3.Dept. Cell and Molecular Biology,G?teborg University,G?teborg,Sweden |
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| Abstract: | Background The pharynx of C. elegans is an epithelial tube whose development has been compared to that of the embryonic heart and the kidney and hence serves
as an interesting model for organ development. Several C. elegans mutants have been reported to exhibit a twisted pharynx phenotype but no careful studies have been made to directly address
this phenomenon. In this study, the twisting mutants dig-1, mig-4, mnm-4 and unc-61 are examined in detail and the nature of the twist is investigated. |
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