Inhibition of apoptosis prevents West Nile virus induced cell death |
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Authors: | Malte C Kleinschmidt Martin Michaelis Henry Ogbomo Hans-Wilhelm Doerr Jr" target="_blank">Jindrich CinatlJr |
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Institution: | (1) Institute for Medical Virology, Johann Wolfgang Goethe-University, Paul-Ehrlich-Str. 40, 60596 Frankfurt am Main, Germany |
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Abstract: | Background West Nile virus (WNV) infection can cause severe meningitis and encephalitis in humans. Apoptosis was recently shown to contribute
to the pathogenesis of WNV encephalitis. Here, we used WNV-infected glioma cells to study WNV-replication and WNV-induced
apoptosis in human brain-derived cells. |
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