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Specie's differences in glutathione-dependent enzymes in the liver and kidney of two fresh water fishes and their implications for cadmium toxicity
Authors:S V S Rana  Rekha Singh
Institution:(1) Toxicology Laboratory, Department of Zoology, Choudhary Charan Singh University, Meerut-250004, India
Abstract:The protective effects of glutathione-dependent enzymes have been studied against cadmium toxicity in the liver and kidney of two fresh water fishesChanna punctatus andClarias batrachus. Specie's differences in the activity of tissue enzymes have also been studied. Cadmium treatment induced lipid peroxidation in the liver and kidney of both species, the kidney being the more susceptible. Enzymological observations revealed thatChanna punctatus is better equipped with conjugating enzymes thanClarias batrachus. Fish having higher activities of these enzymes are thus expected to withstand oxidative stress more effectively.
Keywords:Malondialdehyde  GSH  glutathione-S-transferase  glutathione peroxidase  glutathione reductase
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