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Role of biologically active sphingolipids in tumor growth |
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| Authors: | E. V. Dyatlovitskaya A. G. Kandyba |
| Affiliation: | (1) Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, ul. Miklukho-Maklaya 16/10, 117997 Moscow, Russia |
| Abstract: | This review highlights the literature on the effects of biologically active sphingolipids (sphingosine, ceramide, sphingomyelin, glucosylceramide, gangliosides GM1, GM2, GM3, GD3, etc.) on proliferation, apoptosis, metastases, and invasiveness of tumor cells and the putative role of sphingolipids in chemotherapy of malignant tumors. |
| Keywords: | gangliosides glucosylceramide sphingosine sphingolipids sphingomyelin sphingosine-1-phosphate ceramide tumor |
| 本文献已被 PubMed SpringerLink 等数据库收录！ | |