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The time is right: proteome biology of stem cells
Authors:Whetton Anthony D  Williamson Andrew J K  Krijgsveld Jeroen  Lee Bong Hee  Lemischka Ihor  Oh Steve  Pera Martin  Mummery Christine  Heck Albert J R
Institution:Stem Cell and Leukemia Proteomics Laboratory, Faculty of Medical and Human Sciences, University of Manchester, Christie Hospital, Manchester M20 9BX, UK. awhetton@picr.man.ac.uk
Abstract:In stem cell biology, there is a growing need for advanced technologies that may help to unravel the molecular mechanisms of self-renewal and differentiation. Proteomics, the comprehensive analysis of proteins, is such an emerging technique. To facilitate interactions between specialists in proteomics and stem cell biology,a new initiative has been undertaken, supported by the Human Proteome Organization (HUPO) and the International Society for Stem Cell Research (ISSCR). Here we present the Proteome Biology of Stem Cells Initiative (PBSCI) and report on its goals and future activities.
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