A conserved structure and function of the YidC homologous protein Slr1471 from Synechocystis sp. PCC 6803 |
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Authors: | Sven Gathmann Eva Rupprecht Uwe Kahmann Schneider Dirk |
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Institution: | Fakultat fur Biologie, Universitat Bielefeld, 33594 Bielefeld, Germany. |
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Abstract: | In this article, we show that the orf slr1471 from Synechocystis sp. PCC 6803 codes for a functional member of the YidC/Alb3/Oxa1 protein family, and the encoded protein has a transmembrane topology with a common core structure. Using specific antibodies raised against the Synechocystis YidC homologous protein, we further show that the Synechocystis YidC protein appears to be predominantly localized in the cyanobacterial cytoplasmic membrane. The impact of the described findings for synthesis of membrane proteins and for protein sorting within cyanobacterial cells is discussed. |
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