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电化学免疫传感器在传染病快速检测中的应用
引用本文:林睿,董世彪,卢晓,李杨,郝荣章,宋宏彬. 电化学免疫传感器在传染病快速检测中的应用[J]. 生物技术通讯, 2013, 0(6): 892-895
作者姓名:林睿  董世彪  卢晓  李杨  郝荣章  宋宏彬
作者单位:[1]军事医学科学院疾病预防控制所,北京100071 [2]兰州军区综合训练基地军医训练大队,新疆昌吉831200
基金项目:国家自然科学基金(21105122);北京市自然科学基金(7132164);军事医学科学院创新基金(2012CXJJ018)
摘    要:传染病的快速检测是传染病预防控制的重要环节,其中现场快速检测对于及时有效控制传染病疫情尤为关键。相比于传统检测方法,电化学免疫传感器具有操作简单、快速、灵敏、准确、设备可小型化等优势,可用于传染病快速检测。简要综述了近年来电化学免疫传感器在传染病快速检测中的应用研究进展,重点阐述了该类传感器在现场检测中的主要贡献和不足之处,以及免疫磁分离技术与电化学传感检测相结合在传染病快速检测方面的优势。

关 键 词:电化学免疫传感器  传染病  现场快速检测  免疫磁分离

Application of Electrochemical Immunosensors on Rapid Detection of Infectious Disease
L,N Rui,DONG Shi-Biao,LU Xiao,LI Yang,HAO Rong-Zhang,SONG Hong-Bin. Application of Electrochemical Immunosensors on Rapid Detection of Infectious Disease[J]. Letters in Biotechnology, 2013, 0(6): 892-895
Authors:L  N Rui  DONG Shi-Biao  LU Xiao  LI Yang  HAO Rong-Zhang  SONG Hong-Bin
Affiliation:1. Institute of Disease Control and Prevention, Academy of Military Medical Sciences, Beijing 100071; 2. Medicinae Militaris Training Group, Changji 831200; China)
Abstract:The rapid detection of infectious diseases is of great importance for the prevention and control of these diseases, and the rapid assays available for field detection is particularly important on timely and effectively controlling the infectious diseases. In comparison with traditional methods, the electrochemical inmmno-biosensor (ECIB) has the advantages of simple operation, rapidness, high sensitivity, and miniaturized device, to meet the demands of field detection of infectious diseases. In this review, we presented the recent application of ECIB on rapid detection of infectious diseases, focusing on analyzing the advantages and disadvantages of ECIB on field detection, and the merits of integrating immunomagnetic separation technology with electrochemical immunosensor.
Keywords:electrochemical immunosensor  infectious diseases  rapid field detection  immunomagnetic separation
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