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The influence of 2,4-dichlorophenoxyacetic acid on cell cycle Kinetics and Sister-Chromatid Exchange Frequency in Garlic (Allium sativum L.) Meristem Cells
Authors:J. Doležel  S. Lucretti  F. J. Novák
Affiliation:(1) Institute of Experimental Botany, CS-77200 Olomouc, Czechoslovakia;(2) ENEA -C.R.E., Roma, Casaccia, Italy;(3) IAEA, Vienna, Austria
Abstract:The effect of 2,4-dichlorophenoxyacetic acid (2,4-D) at low concentrations on cell cycle duration and sister-chromatid exchange (SCE) frequency was studied using meristem root-tip cells ofAllium sativum L. 2,4-D induced a marked prolongation of the cell cycle. At the same time, small but statistically significant increases in SCE frequencies were observed at 5 μM and 15 μM 2,4-D concentrations. The significance of these findings in the evaluation of mutagenic activity of 2,4-D is discussed.
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