Chromosomal assignment of seven genes on canine chromosomes by fluorescence in situ hybridization |
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| Authors: | M. L. Guevara-Fujita R. Loechel P. J. Venta V. Yuzbasiyan-Gurkan G. J. Brewer |
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| Affiliation: | (1) Department of Human Genetics, University of Michigan Medical School, 4708 Medical Science Building II, Ann Arbor, Michigan 48109-0618, U.S.A., US;(2) College of Veterinary Medicine, Michigan State University, East Lansing, Michigan, US |
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| Abstract: | Our group has developed more than 600 DNA markers to build a map of the canine genome. Of these markers, 125 correspond to genes (anchor loci). Here we report the first six autosomal genes assigned to canine chromosomes by fluorescence in situ hybridization (FISH), using cosmid DNA: adenine phosphoribosyl transferase on Chromosome (Chr) 3; creatine kinase muscle type on Chr 4; pyruvate kinase liver and red blood cell type on Chr 2; and colony-stimulating factor-1 receptor, glucose transporter protein-2, and tumor protein p53 on Chr 5. These assignments are based on the karytotype proposed by Stone and associates (Genome 34, 407, 1991) using high-resolution techniques. In addition, we have assigned the Menkes gene to the X Chr of the dog. Received: 18 August 1995 / Accepted: 17 November 1995 |
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