Conformation of oligonucleotides in solution from data of the nuclear Overhauser effect

In this review the results of studies of oligonucleotides conformation in solution by 1D and 2D NOE over the last four years are presented. Theoretical basis of 2D NOE and other 2D techniques are briefly considered. The few attempts of determination of oligonucleotides structures in solution on the half-quantitative level and the perspectives of using 2D NOE for quantitative structure resolution are discussed.