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Homozygous mutations in C14orf39/SIX6OS1 cause non-obstructive azoospermia and premature ovarian insufficiency in humans
Authors:Suixing Fan  Yuying Jiao  Ranjha Khan  Xiaohua Jiang  Abdul Rafay Javed  Asim Ali  Huan Zhang  Jianteng Zhou  Muhammad Naeem  Ghulam Murtaza  Yang Li  Gang Yang  Qumar Zaman  Muhammad Zubair  Haiyang Guan  Xingxia Zhang  Hui Ma  Hanwei Jiang  Qinghua Shi
Affiliation:1. Division of Reproduction and Genetics, First Affiliated Hospital of USTC, Hefei National Laboratory for Physical Sciences at Microscale, the CAS Key Laboratory of Innate Immunity and Chronic Disease, School of Basic Medical Sciences, Division of Life Sciences and Medicine, CAS Center for Excellence in Molecular Cell Science, Collaborative Innovation Center of Genetics and Development, University of Science and Technology of China, Hefei 230027, China;2. Medical Genetics Research Laboratory, Department of Biotechnology, Quaid-i-Azam University, Islamabad 45320, Pakistan;3. Shahbaz Sharif District Hospital, Multan 60800, Pakistan
Abstract:
Keywords:mutations  non-obstructive azoospermia  premature ovarian insufficiency  chromosome synapsis  synaptonemal complex
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