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Haploinsufficiency of the Sin3/HDAC corepressor complex member SIN3B causes a syndromic intellectual disability/autism spectrum disorder
Authors:Xenia Latypova  Marie Vincent  Alice Mollé  Oluwadamilare A Adebambo  Cynthia Fourgeux  Tahir N Khan  Alfonso Caro  Monica Rosello  Carmen Orellana  Dmitriy Niyazov  Damien Lederer  Marie Deprez  Yline Capri  Peter Kannu  Anne Claude Tabet  Jonathan Levy  Emmelien Aten  Nicolette den Hollander  Bertrand Isidor
Institution:1. Service de Génétique Médicale, CHU Nantes, 9 quai Moncousu, 44093 Nantes Cedex 1, France;2. Center for Human Disease Modeling, Duke University Medical Center, Durham, NC 27701, USA;3. L’Institut du Thorax, INSERM, CNRS, Université de Nantes, 44007 Nantes, France;4. Université de Nantes, CHU Nantes, Inserm, Centre de Recherche en Transplantation et Immunologie, UMR 1064, ITUN, 44000 Nantes, France;5. Department of Biological Sciences, National University of Medical Sciences, 46000 Rawalpindi, Pakistan;6. Unidad de Genética, Grupo de Investigación Traslacional en Genética, Hospital Universitario y Politécnico La Fe, 46026 Valencia, Spain;7. Department of Pediatrics, Ochsner Clinic, New Orleans, LA 70128, USA;8. Centre de Génétique Humaine, IPG, 6041 Gosselies, Belgium;9. Service de Neuropédiatrie, Clinique Saint Elizabeth, 5000 Namur, Belgium;10. Service de Génétique Médicale, Hôpital Robert Debré, 75019 Paris, France;11. Division of Clinical and Metabolic Genetics, The Hospital for Sick Children, Toronto, ON M5G 1X8, Canada;12. Service de Cytogénétique, Hôpital Robert Debré, 75019 Paris, France;13. Department of Clinical Genetics, Leiden University Medical Center, 2333 Leiden, the Netherlands;14. Northern Genetics Service, Institute of Genetic Medicine, Newcastle Upon Tyne NE1 3BZ, UK;15. Kingston General Hospital Research Institute, 76 Stuart Street, Kingston, ON K7L 2V7, Canada;16. Clinical Genetics, Dell Children’s Medical Group, Austin, TX 78731, USA;17. Department of Molecular and Human Genetics, Baylor College of Medicine, Houston, TX 77030, USA;18. GeneDx, 207 Perry Parkway, Gaithersburg, MD 20877, USA;19. Greenwood Genetic Center, 106 Gregor Mendel Cir, Greenwood, SC 29646, USA;20. Sainte-Justine Hospital, 3175, Cote-Sainte-Catherine, Montreal, QC, Canada;21. Etablissement Français du Sang, 44000 Nantes, France;22. CRCINA, INSERM, CNRS, Université d’Angers, Université de Nantes, 44000 Nantes, France;23. LabEx IGO, Nantes 44000, France;24. Rosalind & Morris Goodman Cancer Research Center and Department of Medicine, McGill University, Montreal, QC H3A 1A3, Canada;25. Advanced Center for Translational and Genetic Medicine, Stanley Manne Children’s Research Institute, Ann & Robert H. Lurie Children’s Hospital of Chicago, Chicago, IL 60611, USA;26. Department of Pediatrics, Feinberg School of Medicine, Northwestern University, Chicago, IL 60611, USA
Abstract:
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