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A Recombinant Avian Leukosis Virus Subgroup J for Directly Monitoring Viral Infection and the Selection of Neutralizing Antibodies |
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| Authors: | Qi Wang Xiaofei Li Xiaolin Ji Jingfei Wang Nan Shen Yulong Gao Xiaole Qi Yongqiang Wang Honglei Gao Shide Zhang Xiaomei Wang |
| Abstract: | Avian leukosis virus subgroup J (ALV-J) has induced serious clinical outbreaks and has become a serious infectious disease of chickens in China. We describe here the creation of a recombinant ALV-J tagged with the enhanced green fluorescent protein (named rHPRS-103EGFP). We successfully utilize the rHPRS-103EGFP to visualize viral infection and for development of a simplified serum-neutralization test. |
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