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Continued development of an empirical function for predicting and rationalizing protein–protein binding affinities

Authors:	Joseph Audie

Institution:	Department of Chemistry, Sacred Heart University, Fairfield, CT 06825, United States; CMD Bioscience, Orange, CT, United States

Abstract:

Keywords:	Protein&ndash protein recognition Binding affinity Free energy Alanine scanning mutagenesis Hot spot Peptide therapeutics Biologics Computational
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