产前胎儿磁共振成像的临床应用及研究进展

出生缺陷已经成为影响我国人口素质的重要卫生问题,产前诊断是减少患儿出生缺陷的有效预防手段和措施。作为产前超声诊断重要补充的手段,胎儿MRI检查具有多方位、多参数、高质量、大视野成像的特点。尤其在中枢神经系统方面具有US无法比拟的优势,随着宫内治疗技术的开展和提高,其潜在的价值和应用前景越来越明显。近年来,随着各种快速MR成像方法的应用,胎儿MRI研究有了很大进步,不仅能有效地评估胎儿的正常解剖、发育变异及病理改变,而且功能MRI也正积极尝试用于胎儿正常发育及疾病的研究中。正硝地解释胎儿MRI的影像学表现仍是今后一段时间内胎儿MRI研究的方向。客观地认识MRI在产前检查中的优势与劣势、合理地应用不同的成像序列,有利于更准确地检出病变。

Application and Development of Fetal Magnetic Resonance Imaging

Birth defect has become a significance public health issue influencing the quality of Chinese population.Ultrasonog- raphy is the primary prenatal screening modality used in the evaluation of the fetus and the maternal pelvis.As an important complemen- tary method of prenatal ultrasound in the evaluation of the fetus with suspected abnormalities,fetal magnetic resonance imaging(MRI) plays a complementary role,with advantages of many directions,multiparameters,excellent tissue contrast and a large field of view.Es- pecially in central nervous system,the potential value and application prospects is getting more and more obvious.Recently,not only MRI can evaluate effectively fetal normal dissection,the mutation of development and the change of pathology,but also functional MRI is being tried to br used in fetus normal development and disease researches.Correctly explaining fetus MRI findings is still the subject of fetus MRI study in the near future.So the advantages and disadvantages of MRI in the prenatal examination should be objectively real- ized;different imaging sequences should be reasonably applied,which will help detect fetus lesions more accurately.