Involvement of an SCF<Superscript>Slmb</Superscript> complex in timely elimination of E2F upon initiation of DNA replication in <Emphasis Type="Italic">Drosophila</Emphasis>期刊界 All Journals 搜尽天下杂志传播学术成果专业期刊搜索期刊信息化学术搜索

Involvement of an SCFSlmb complex in timely elimination of E2F upon initiation of DNA replication in Drosophila

Authors:	Jean-Karim?Hériché,Dan?Ang,Ethan?Bier,Patrick?H?O'Farrell author-information" > author-information__contact u-icon-before" > mailto:ofarrell@cgl.ucsf.edu" title=" ofarrell@cgl.ucsf.edu" itemprop=" email" data-track=" click" data-track-action=" Email author" data-track-label=" " >Email author

Affiliation:	(1) Department of Biochemistry and Biophysics, University of California, San Francisco 513 Parnassus Street, San Francisco, CA 94143-0448, USA;(2) Section of Cell and Developmental Biology, University of California, San Diego, 9500 Gilman Drive, La Jolla, CA 92093-0349, USA

Abstract:	Background Cul1 is a core component of the evolutionarily conserved SCF-type ubiquitin ligases that target specific proteins for destruction. SCF action contributes to cell cycle progression but few of the key targets of its action have been identified.

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