Rat heart cell membranes contain three substrates for cholera toxin-catalyzed ADP-ribosylation and a single substrate for pertussis toxin-catalyzed ADP-ribosylation |
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| Authors: | T Murakami H Yasuda |
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| Institution: | 1. Medical Microbiology Residency Programme, Oman Medical Specialty Board, Muscat, Oman;2. Department of Microbiology and Immunology, Sultan Qaboos University Hospital, Muscat, Oman;3. Department of Microbiology, The Royal Hospital, Muscat, Oman |
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| Abstract: | Three peptides (Mr = 45,000, 47,000 and 52,000) in the cholate extract from rat heart cell membranes were radiolabeled when the extract was incubated in the presence of activated cholera toxin and 32P]NAD. A single peptide of Mr = 41,000 in this extract was ADP-ribosylated by pertussis toxin in the presence of 32P]NAD. |
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