NALL-1, an acute lymphoblastic leukemia cell line with peroxidase activity |
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| Authors: | Joseph Yourno William A. Samsonoff Ann Willey Peter Burkhart Frank Lizzi Anthony Tartaglia |
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| Affiliation: | (1) Center for Laboratories and Research, New York State Department of Health, Albany, New York;(2) Hematology Division, St. Peter's Hospital, Albany, New York |
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| Abstract: | Summary All cells examined from the non-B, non-T acute lymphoblastic leukemia cell line, NALL-1, stained positive both for terminal deoxynucleotidyl transferase and for common ALL antigen. In addition, peroxidase activity was detected by light microscopy in 55 to 75% of cells and peroxidase-positive granules were detected ultrastructurally in >80% of cells. Peroxidase activity in NALL-1 may result from derepression of peroxidase genes or clonal proliferation of a biphenotypic precursor cell. |
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| Keywords: | NALL-1 ALL peroxidase |
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