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Upregulation of ATG7 attenuates motor neuron dysfunction associated with depletion of TARDBP/TDP-43
Authors:Aneesh Donde  Mingkuan Sun  Yun Ha Jeong  Xinrui Wen  Jonathan Ling  Sophie Lin
Institution:1. Departments of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USA;2. Neuroscience, Johns Hopkins University School of Medicine, Baltimore, MD, USAORCID Iconhttps://orcid.org/0000-0002-0917-9436;3. Departments of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USAORCID Iconhttps://orcid.org/0000-0002-4511-5894;4. Department of Neural Development and Disease, Korea Brain Research Institute (KBRI), Daegu, Korea;5. Departments of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USAORCID Iconhttps://orcid.org/0000-0003-2667-2983;6. Departments of Pathology, Johns Hopkins University School of Medicine, Baltimore, MD, USAORCID Iconhttps://orcid.org/0000-0003-1927-9729
Abstract:
Keywords:ALS  ATG7  autophagy  Drosophila  frontotemporal dementia  mouse  SQSTM1/p62  TARDBP/TDP-43
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