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The use of a transesterification technique to distinguish between certain neuraminidase resistant epithelial mucins
Authors:Dr P E Reid  C F A Culling  W L Dunn  M G Clay
Institution:(1) Present address: Department of Pathology Faculty of Medicine, University of British Columbia, Vancouver, B.C., Canada;(2) Department of Surgery, Faculty of Medicine, University of British Columbia, Vancouver, B.C., Canada
Abstract:Summary The effects of potassium hydroxide and sodium methoxide treatments upon the Alcian blue staining and neuraminidase lability of certain neuraminidase resistant epithelial mucins have been studied. The results were interpreted as indicating that while the mucins of rat colon and rabbit Brunner's gland contain only 4-O-acetyl sialic acid, human colonic epithelial mucins may contain some sialic acid with esters at the C1 carboxyl group. Supported by the Medical Research Council of Canada Grant MA 4376.
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