Aromatic amino acid biosynthesis in Trichophyton rubrum |
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Authors: | R A Zussman E E Vicher I Lyon |
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Institution: | (1) University of Illinois at the Medical Center and Chicago Medical School, Chicago, Illinois;(2) Present address: Abbot Laboratories, North Chicago, Illinois |
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Abstract: | Summary WhenTrichophyton rubrum is grown in a minimal medium containing glucose, the carbon skeleton of fungal phenylalanine and tyrosine is derived from the glucose carbon. Tracer experiments with variously labeled glucose-C14 indicate that phenylalanine synthesis is linked to glycolysis, but suggest that the pentose phosphate pathway is not involved. These findings suggest that aromatic amino acid biosynthesis may not be linked to the shikimic acid pathway inT. rubrum. |
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