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Leptospira Seroprevalence and Risk Factors in Health Centre Patients in Hoima District,Western Uganda
Authors:Anou Dreyfus  Jonathan W. Dyal  Raewynne Pearson  Clovice Kankya  Charles Kajura  Lordrick Alinaitwe  Steven Kakooza  Katharine M. Pelican  Dominic A. Travis  Michael Mahero  David R. Boulware  Lawrence Mugisha
Abstract:BackgroundThe burden of human leptospirosis in Uganda is unknown. We estimated the seroprevalence of Leptospira antibodies, probable acute/recent leptospirosis, and risk factors for seropositivity in humans in rural Western Uganda.Conclusions/SignificanceThe 35% prevalence of Leptospira antibodies suggests that exposure to leptospirosis is common in rural Uganda, in particular the Nigeria serovar (Pyrogenes serogroup). Leptospirosis should be a diagnostic consideration in febrile illness and “smear-negative malaria” in rural East Africa.
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