Netilmicin in the treatment of bacterial respiratory tract infections |
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Authors: | M Wandzilak P G?uszko W Królikowski A Prokop J Soja A Szczeklik |
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Institution: | Kliniki Alergii i Immunologii. |
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Abstract: | Netilmicin - a semisynthetic aminoglycoside - was administered to 33 patients with the acute or chronic lower respiratory tract or pulmonary infections in a daily dose of 5 mg/kg body weight for 10 days. A principle criterium of patients classification to netilmicin therapy were sensitive bacterial strains either in sputum or in BAL liquid. A significant clinical improvement was noted in 88% of the treated patients. However, elimination of pathogens from the sputum was achieved only in 52% of these patients. No improvement was observed in 4% of the treated patients. No adverse reactions were noted. Netilmicin proved safe and effective antibacterial agent in patients with respiratory infections. |
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