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Chemical constituents from the calyces of Physalis alkekengi var. franchetii
Institution:1. Department of Natural Products Chemistry, School of Traditional Chinese Materia Medica, Key Laboratory of Structure-Based Drug Design & Discovery, Ministry of Education, Shenyang Pharmaceutical University, Shenyang 110016, China;2. Institute of Traditional Chinese Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 300193, China;1. Institute of Marine Biology & Natural Products, Ocean College, Zhejiang University, Zijingang Campus, No. 866 Yuhangtang Road, Hangzhou 310058, PR China;2. Zhejiang Key Laboratory of Gastro-Intestinal Pathophysiology, Zhejiang Hospital of Traditional Chinese Medicine, Zhejiang Chinese Medical University, No. 54 Youdian Road, Hangzhou 310006, PR China;3. Zhejiang Institute for Drug Control, No. 86 Jichang Road, Hangzhou 310004, PR China;4. Zhejiang Provincial People''s Hospital, No. 158 Shangtang Rd., Hangzhou 310014, China;1. Federal University of Pará, Institute of Biological Sciences, Laboratory of Parasitology and Laboratory of Structural Biology, Belém, Pará, Brazil;2. National Institute of Science and Technology in Structural Biology and Bioimaging, Rio de Janeiro, Rio de Janeiro, Brazil;3. Evandro Chagas Institute, Laboratory of Electron Microscopy, Department of Health Surveillance, Ministry of Health, Belém, Pará, Brazil;4. Federal University of Pará, Institute of Biological Sciences, Laboratory of Neurochemistry Molecular and Cellular, Belém, Pará, Brazil;1. Instituto de Química, Universidad Nacional Autónoma de México, Circuito Exterior, Ciudad Universitaria, Coyoacán 04510, D.F., Mexico;2. Facultad de Ciencias Naturales, Universidad Autónoma de Querétaro, Avenida de las Ciencias s/n, Col. Juriquilla, 76230 Querétaro, Qro, Mexico;1. Mientrung Institute for Scientific Research (MISR), Vietnam Academy of Science and Technology, 321 Huynh Thuc Khang, Hue City, Thua Thien Hue 531600, Viet Nam;2. Graduated University of Science and Technology, 18 Hoang Quoc Viet, Cau Giay District, Ha Noi 122300, Viet Nam;3. Institute of Marine Biochemistry (IMBC), Vietnam Academy of Science and Technology, 18 Hoang Quoc Viet, Cau Giay District, Ha Noi 122300, Viet Nam;4. Thaibinh University of Medicine and Pharmacy, 373 Ly Bon, Thai Binh City, Thai Binh 410000, Viet Nam;5. Thanh Hoa Sports and Physical Education College, 24 Hoang Van Thu, Thanh Hoa City, Thanh Hoa 441300, Viet Nam;6. Medicinal Chemistry Division, Faculty of Chemistry, University of Science, Vietnam National University Hochiminh City, 227 Nguyen Van Cu, District 5, Hochiminh City 748000, Viet Nam;1. College of Pharmacy, Dongguk University-Seoul, Goyang, Gyeonggi-do 10326, Republic of Korea;2. College of Pharmacy and BK-Plus Team, Dongguk University-Seoul, Goyang, Gyeonggi-do 10326, Republic of Korea
Abstract:One new monoterpenoid glycoside (1), together with seven known compounds, including two alkaloids (23), three phenylpropanoids (46), and two nucleosides (78) were isolated from the calyces of Physalis alkekengi var. franchetii. Their structures were elucidated by a combination of detailed spectroscopic analyses, chemical methods, and comparison with reported data. These eight compounds were isolated for the first time from the genus Physalis. The chemotaxonomic significance of these compounds was summarized.
Keywords:Calyces  Monoterpenoid glycoside  Alkaloids  Phenylpropanoids
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