Lipid composition of photoreceptor membranes from goldfish retinas |
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Authors: | Steven J Fliesler Maureen B Maude Robert E Anderson |
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Institution: | Cullen Eye Institute and Program in Neuroscience, Baylor College of Medicine, Texas Medical Center, Houston, TX 77030 U.S.A. |
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Abstract: | Isolation and biochemical characterization of goldfish retinal photoreceptor outer segment membranes are described. The lipid fraction is composed primarily of phospholipids (68 mol%) with substantial amounts of neutral lipids (32 mol%). Sterols account for only about 2 wt% of the membranes (about 9 mol% of the total lipids). The phospholipid class composition and fatty acid composition are similar to those of other vertebrate photoreceptor membranes. Two novel findings were the high levels of free fatty acids (21 mol% of the total lipids, primarily palmitic and docosahexaenoic acids) and the presence of relatively significant amounts of a C-32 diacylglycerol molecular species. |
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Keywords: | Photoreceptor membrane Rod outer segment Lipid composition Retina (Goldfish) |
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