ANTIHISTAMINE IN THE PREVENTION OF SERUM REACTION FOLLOWING INJECTION OF TETANUS ANTITOXIN

Of 100 patients given tetanus antitoxin, 56 were given an antihistaminic drug in oral doses of 50 mg. daily for ten days following injection. The other 44 were not given antihistamine. The incidence of serum reaction in the former group was 3.6 per cent; in the latter, 20.4 per cent.