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Engineering of Penicillium chrysogenum for fermentative production of a novel carbamoylated cephem antibiotic precursor
Authors:Diana M Harris  Ilja Westerlaken  Dick Schipper  Zita A van der Krogt  Andreas K Gombert  John Sutherland  Leonie M Raamsdonk  Marco A van den Berg  Roel AL Bovenberg  Jack T Pronk  Jean-Marc Daran
Institution:1. Department of Biotechnology, Delft University of Technology, Julianalaan 67, 2628BC, Delft, The Netherlands;2. Kluyver Centre for Genomics of Industrial Fermentation, Julianalaan 67, 2628BC, Delft, The Netherlands;3. DSM Food Specialties, DFS/R&D/Biochemistry, DSM Gist (699-0330), P.O. Box 1, 2600 MA, Delft, The Netherlands;4. DSM Food Specialties, DFS/R&D/ANA, DSM Gist (624-0305), P.O. Box 1, 2600 MA, Delft, The Netherlands;5. School of Chemistry, University of Manchester, Oxford Road, Manchester M13 9PL, UK;6. DSM Anti-Infectives, DAI/INNO, DSM Gist (624-0270), P.O. Box 425, 2600 AK, Delft, The Netherlands;1. State key laboratory of Bioreactor Engineering, East China University of Science and Technology (ECUST), Shanghai, People’s Republic of China;2. DSM Biotechnology Center, Delft, the Netherlands;3. Department of Biotechnology, Delft University of Technology, Delft, the Netherlands;1. Institute of Biotechnology of León (INBIOTEC), Av. Real s/n, 24006 León, Spain;2. Area of Microbiology, Department of Molecular Biology, University of León, Campus de Vegazana s/n, 24071 León, Spain;1. Departamento de Biología Molecular, Universidad de León, León, Spain;2. Infobiotics Consulting SL, León, Spain
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