Population study of the Udmurt population: Analysis of ten polymorphic DNA loci of the nuclear genome |
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| Authors: | M. A. Bermisheva N. V. Petrova R. A. Zinchenko E. E. Timkovskaya P. Yu. Malyshev S. G. Gavrilina E. K. Ginter E. K. Khusnutdinova |
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| Affiliation: | (1) Institute of Biochemistry and Genetics, Russian Academy of Sciences, Ufa Research Center, Ufa, 450054, Russia;(2) Medical Center for Genetic Research, Russian Academy of Medical Sciences, Moscow, 115478, Russia |
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| Abstract: | Genetic structure of Southern and Northern ethnographic groups of the Udmurt population from six regions of the Republic of Udmurtia has been studied. All the samples were examined using ten polymorphic DNA loci: VNTR/PAH, VNTR/ApoB, VNTR/DATI, VNTR/eNOS, ACE, CCR5 Δ32, KM19, IVS6a, THOI, and FABP2. Allelic and genotype frequencies were estimated for each of the six populations. The average heterozygosity for these ten polymorphic loci varied from 0.47 in Udmurts from Glazovskii region to 0.53 in Udmurts from Malopurginskii region. The level of genetic variation (F ST) between populations of Udmurts was 0.0048. Ethnographic subdivision of the population into Northern and Southern Udmurts is in good agreement with the values of genetic distances and phylogenetic analysis. |
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