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Chemical synthesis of the S‐linked glycopeptide,sublancin |
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| Authors: | Hidekazu Katayama Yuya Asahina Hironobu Hojo |
| Affiliation: | 1. Department of Applied Biochemistry, School of Engineering, Tokai University, , Hiratsuka, Kanagawa, Japan;2. Graduate School of Science and Technology,, Tokai University, , Hiratsuka, Kanagawa, Japan;3. Institute of Glycoscience, Tokai University, , Hiratsuka, Kanagawa, 259‐1292 Japan |
| Abstract: | Sublancin is an S‐linked glycopeptide produced by Bacillus subtilis 168 and consists of 37 amino acid residues with two disulfide bonds. In this study, we synthesized sublancin by Fmoc‐based solid‐phase peptide synthesis and chemoselective disulfide formation reactions. Copyright © 2011 European Peptide Society and John Wiley & Sons, Ltd. |
| Keywords: | S‐linked glycopeptide sublancin solid‐phase peptide synthesis disulfide bond |