A review of the role of 70 kDa heat shock proteins in protein translocation across membranes |
| |
| Authors: | Elizabeth Craig Pil Jung Kang Will Boorstein |
| |
| Affiliation: | (1) Department of Physiological Chemistry, University of Wisconsin-Madison, 53706 Madison, Wisconsin, USA |
| |
| Abstract: | Summary The compartmentalization of essential hsp70 proteins indicates that hsp70s carry out crucial functions in several compartments of the cell. The use of conditional mutants has allowed study of the cellular processes that require hsp70 function. For efficient translocation of proteins across membranes hsp70s are required in the cytoplasm, as well as in the matrix of mitochondria and in the lumen of the endoplasmic reticulum. |
| |
| Keywords: | |
| 本文献已被 SpringerLink 等数据库收录！ |
