| DNA疫苗的转染载体及免疫途径 |
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| 引用本文： | 王明连,李劲松. DNA疫苗的转染载体及免疫途径[J]. 生物技术通讯, 2002, 13(2): S004-S006 |
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| 作者姓名： | 王明连 李劲松 |
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| 作者单位： | 北京微生物流行病学研究所,北京100071 |
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| 摘 要： | 本介绍了阳离子脂质体、聚合胺、减毒侵袭性细菌、Cochleates等可介导疫苗DNA转染的载体，并对肌肉注射、基因枪导入、皮内皮下注射及粘膜接种等可用以DNA疫苗接种的几种免疫途径作一简述。
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| 关 键 词： | 基因免疫 DNA疫苗 转染载体 免疫途径 |
| 文章编号： | 1009-0002(2002)02-00S4-03 |
| 修稿时间： | 2001-08-20 |
TranSection vehicles and inoculation methods of DNA vaccine |
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| WANG Ming-lian,LI Jin-song. TranSection vehicles and inoculation methods of DNA vaccine[J]. Letters in Biotechnology, 2002, 13(2): S004-S006 |
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| Authors: | WANG Ming-lian LI Jin-song |
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| Abstract: | Cationic lipisome,polyamine,attenuated invasive microbes and Cochleates may act as transfection vehicle of DNA vaccines for they protect DNA from being degraded and enhance transfection proficiency.Intramuscular in-jection,gene gun,intradermal or subcutaneous injection,and mucosal inoculation may be used in DNA vaccination. |
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| Keywords: | genetic immunization DNA vaccine transfection vehicle inoculation method |
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