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Activity of arylamidases in serum during normal pregnancy.
Authors:E Wieczorek  K A Sobiech
Abstract:Activity of arylamidases toward 6 beta-naphthylamides of L-amino acids was studied in the blood serum from 110 healthy women between the 6th and 36th weeks of pregnancy. A regular increase in the enzymatic activity was demonstrated toward all substrates under examination, particularly in the presence of alanyl-, leucyl- and lysyl-beta-naphthylamides, most pronounced in the last trimester of gestation. A correlation between oxytocinase and arylamidases activity was demonstrated, suggesting a possibility of using the enzymatic measurement as a diagnostic test in the normal course of pregnancy.
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