Staphylococcus aureus immunodominant surface antigen B is a cell-surface associated nucleic acid binding protein |
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| Authors: | Nicole M Mackey-Lawrence Denise E Potter Nuno Cerca Kimberly K Jefferson |
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| Affiliation: | (1) Department of Microbiology and Immunology, Virginia Commonwealth University, Richmond, Virginia, 23298, USA |
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| Abstract: | Background Staphylococcus aureus immunodominant surface antigen B (IsaB) elicits an immune response during septicemia and is generally classified as a virulence factor, but its biological function remains completely undefined. In an attempt to identify staphylococcal RNA-binding proteins, we designed an RNA Affinity Chromatography assay and subsequently isolated IsaB. |
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